Vape Nicotine: How much nicotine is in a vape? Vaping Devices (Electronic Cigarettes) DrugFacts National Institute on Drug Abuse (NIDA) Electronic Nicotine Delivery Systems (ENDS), including e cigarettes and vapes, are often perceived as a safer alternative to traditional tobacco. But is the evidence really supporting this belief? A recent umbrella review published Vaping vs Smoking How BOTH Harm Your Mouth, Gums & Teeth