FDA Tobacco Education & Prevention Resources: Posters, Flyers, & More How Vapes Work Vaping is the act of inhaling a heated, aerosolized substance. It is critical to distinguish vaping from smoking. Smoking is the inhalation of a burned substance. The main difference between the two Electronic Cigarettes and Cardiovascular Risk Smoking E Cigarettes: Patent Analysis and Technological Evolution by Copperpod IP Medium